Working on a train with a laptop you soon get to learn that using a mouse is very unproductive.  Certainly on the trains in the UK your continually jossled by ropey train tracks or the person crammed in next to you.

I've taken to trying to learn a new shortcut key every day in visual studio and to aid in this I've found a handy switch that in 2005 at least is switched off by default.  On the Tools/Customize screen theres a checkbox called "Show shortcut keys in ScreenTips", switch this on and next time you mouse to a toolbar you'll have the opportunity to learn that function.  Ctrl KK, KN, KP have saved me so much time over using the bookmark buttons. 

I've also remapped a few keys, particularly the Ctrl Up and Ctrl Down to take you to the top of your current or next method when in text editing mode, much better than scrolling the screen a line at a time which is there default operation.